Karlo M. Lopez Howard Hughes Medical Institute Post-Doctoral Fellow Pomona College

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E-mail: karlo.lopez@pomona.edu Office: Seaver North, Room 27 Laboratory: Seaver North, Room 16 Telephone: Office: (909) 607-9616 Lab: (909) 607-9613 Fax:  (909) 607-7726 Chemistry Department home page Pomona College home page

Dr. Sazinsky joined the department in July 2007 to teachcourses in Organic and Biological Chemistry. His research activities employ X-ray crystallography andbiochemical techniques as primary tools to answer important questions about thestructure and function of proteins. The major research themes are to identify the determinants ofmetalloenzyme activity and tuning, re-engineer proteins for altered functionsand/or expanded catalytic capabilities, and to provide a basis forunderstanding the biochemical processes in pathogenic bacteria. Undergraduateresearch students are heavily involved in the structural and biochemicalcharacterization of specific protein targets.

Matt received a B.S. in chemistry in 1995 from HaverfordCollege, where he was introduced to bioinorganic chemistry by Robert C.Scarrow. He conducted his graduate work at MIT under the guidance of Stephen J.Lippard and earned his Ph. D. in 2004 after investigating the structures ofbacterial multicomponent monooxygenases. As an NRSA post-doctorial fellow at Northwestern University in AmyRosenzweig’s laboratory, he worked on copper homeostasis and membrane proteinbiochemistry.

Follow thelinks above for course related material or for further information about hisresearch program.