Class Playing Krebs Cycle Poker, Feb, 2006

Exam 1 review:  Introduction to Biochemistry 147 Intro2  Intro3 Glycolysis Tri Carboxylic Acid Cycle  Electron Transport/OxPhos  Exam 2 review: Central Metab Related  Photosynthesis   Fatty Acid Metabolism  Exam 3 review: Other Lipids   Nitrogen Metabolism  Amino Acids    Nucleotides  

additional material after Exam 3: Hormonal regulation     Macromolecular Anabolism/Replication   Transcription   Protein Biosynthesis  Protein Catabolism

Lab information: Background presentation 

This project on yeast models of human genetic disease is based on analysis of current status of metabolic genes cited in this paper:

Francoise Foury, Human Gene Diseases: A Cross-Talk between Man and Yeast.  Gene 195 (1997):1-10.  

You can get this pdf from the PubMed database on the Library website.  A list of the most relevant metabolic genes from this paper, with yeast and human homologs, is here.  A list of the things you need to put on your web page about your human metabolic genetic disease gene and its yeast homolog can be found here. You can find out about the yeast genes here: http://www.yeastgenome.org/

You can find out about human genes by reading references in PubMed and by looking at OMIM: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM

 2006 pages:

            Adenosine Deaminase enzyme, Jacqueline King

            Glucose 6 Phosphate Dehydrogenase enzyme, Caroline King

            Pyruvate Carboxylase enzyme, David McCormick

            Alpha Keto Glutarate Dehydrogenase enzyme, Mariko Yamazaki

            Pyruvate Kinase enzyme, Ellen Perkins

            Pyruvate Dehydrogenase enzyme, Allison Moser

            Fumarate Hydratase enzyme, Sarah Dumas

           Arginio Succinate Synthetase, Aaron Cooper

  2007 pages are under construction and will appear later.

-  Lab Data Collection: Excel Worksheet