Module 1: Spot gridding and fold-change selection
Module 2: Normalization of microarray data
Module 3: Clustering, comparison, prediction, and GO term analysis
For questions about the biology modules and/or examples of student responses to the questions asked within the modules, please contact:
Halstead-Bent Professor of Biology
Module 1: Spot gridding and segmentation
Module 2: Downloading data from Stanford Microarray Database
Module 5: Hierarchical clustering
Module 6: Prediction Analysis for Microarrays (PAM) classification
For questions about the statistics modules and/or examples of student responses to the questions asked within the modules, please contact:
Assistant Professor of Mathematics
modules were originally created as part of a Howard Hughes Medical Institute
We have designed the modules so that they can all be used in a single class or used individually for a course or half-course. Additionally, we have modified the modules slightly for use in either a biology or statistics course.
The modules are described in some detail in:
J. Hardin, L. Hoopes, R. Murphy; Analyzing DNA Microarrays with Undergraduate Statisticians, Proceedings of the Seventh International Conference on Teaching Statistics, 2006.
This work would not have been possible without generous funding by grants from the Howard Hughes Medical Institute and the NSF Major Research Instrumentation program.