Publications by Laura Livingston Mays Hoopes



L. L. Mays.  Genetics, a Molecular Approach.  Macmillan, New York, 1981.  A 16 chapter advanced undergraduate textbook.


L. Hoopes, editor.  Research in Biology at Private Undergraduate Institutions.  Council on Undergraduate Research, Tucson, AZ, 1986.


M M Allen and L Hoopes, editors, with statistical analysis by M. T. Hoopes.  Research in Biology at Primarily Undergraduate Institutions, second edition.  Council on Undergraduate Research, Tucson, AZ, 1989.


L Hoopes editorial consultant.  Magill’s Survey of Sciences: Life Science. Salem Press, Pasadena, CA 1991, 6 volumes.


Laura L. Mays Hoopes, Breaking Through the Spiral Ceiling: An American Woman Becomes a DNA Scientist.  Under serious consideration at a major

university press.


Laura L. Mays Hoopes, The Bad Project. About 2/3 finished, novel about college life of two first year students at a fictional excellent small college. 


Refereed Original Scientific Articles (* indicates undergraduate coauthor):


In preparation for Nature Genetics: Ann Feng Zhao*, Janice Joo*, Jocelyn Young*, Rachel Allen*,Vinita Lukose*, Laty Cahoon, Stephanie De Santiago*, Michelle Wu, Kyle Lancaster*, Meghan McFarlane*, Beth Rockmill (Yale University), and Laura L. Mays Hoopes.  Resetting the yeast replicative aging clock in meiotic prophase.


Gloria Yiu*,  Alejandra McCord*, Laty Cahoon, Alison Wise*, Rishi Jindal*, Jennifer Hardee*, Allen Kuo*, Michelle Yuen Shimogawa*, Michelle Wu, John Kloke, Johanna Hardin, and Laura L. Mays Hoopes.  Gene Expression During Replicative Aging in Yeast. J Gerontology :Biological Sciences 63A (1):21-34 (2008.)


Todd Eckdahl, Adam Brown, Steven Hart, Kelly Malloy, Laurie Heyer, Martha Shott, Laura L. Mays Hoopes, Gloria Yiu*, Laurie Heyer. Microarray analysis of the in vivo sequence preferences of a minor groove binding drug  BMC Genomics. (2008), 9:32-44. Online availability at


Johanna Hardin, Laura Hoopes, and Ryan Murphy*. Analyzing DNA Microarrays with Undergraduate Statisticians.  ICOTS 7 (2006) 13E (Multivariate Statistics) 1-5 (refereed, published online); can be downloaded at:


Alison Wise*, Jo Hardin, Laura Hoopes.  Yeast through the ages: A statistical analysis of genetic changes in yeast aging. Chance (Publication of the American Statistical Association) 19 (3): 39-44, 2006. Cover article.


Campbell AM, Eckdahl TT, Fowlks E, Heyer LJ, Hoopes LLM, Ledbetter ML, and Rosenwald A.  Genome Consortium for Active Teaching (GCAT). (2006) Science 311:110-111.


William D.Bradford*, Laty Cahoon, Sara R. Freel*, Laura L. Mays Hoopes, Todd T. Eckdahl.  Assessment of the Reliability and Convenience of an Inexpensive, Gel Electrophoresis-Based PCR Method for Quantifying mRNA Levels; Cell Biology Education online journal Summer, 2005, 4:157-68, .


Hoopes, LLM, Jindal, R*, Hardee, J*, Wu, M, Shimogawa, MY*, Kuo, A*, and Hardin, J. Microarray Analysis of Yeast Aging to 12 Generations.  Short meeting report, February 3, 2004,


Weitao, T, Budd, M, Mays Hoopes, LL, and Campbell, JL.  DNA2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of Saccharomyces cerevisiae.  J Biol Chem  278(25):22513-22 (2003).


Versini, G, Comet, I, Wu, M, Hoopes, L, Schwob, E, and Pasero, P .  The yeast Sgs1 helicase is differentially regulated for genomic and ribosomal DNA replication.  EMBO J 22:1939-1949 (2003).


Hoopes, Laura L M, Budd, M, Choe, W, Weitao, T and Campbell, JL.  Mutations in DNA replication genes reduce yeast life span.  Molecular and Cellular Biology 22:4126-4146 (2002).  (Acknowledgement to Meghan McFarlane* and Jessica Brown*).


Choe, W, Budd, M, Imamura, O, Hoopes, L and Campbell, JL. Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication.  Molecular and Cellular Biology 22:4202-4217 (2002).


Hoopes, Laura LM,   Bolen, J., Riggs, Art, and Singer-Sam, Judith. (1995) Preparation of spermatogonia, spermatocytes, and round spermatids for analysis of gene expression using Fluorescence-Activated Cell Sorting.   Biology of Reproduction 53:1003-1011.


Abrams, J.*, Reinys, T.*, and Kim, J.* (faculty advisor L. Hoopes).  DNA methylation and magnesium concentration interact in regulating DNA flexibility.  Proceedings, National Conference on Undergraduate Research V, 686-691 (1991).


Hoopes, LLM, Jennings, M,  Spuck, L.,  Chao*, W, and Nelson, J. (1990).  DNA methylation in aging mouse liver.  ICN Symposium, Molecular Biology of Aging, pp 341-349, Alan R. Liss, Inc., New York.


Howlett, D*., Dalrymple, S*., and Mays-Hoopes, LL. (1989).  Age related demethylation of mouse satellite DNA is easily detectable by HPLC but not by restriction endonucleases.  Mutation Res. 219:101-106.


Singhal, R., Mays-Hoopes, LL, and Eichhorn, G. (1987).  DNA methylation in aging of mice.  Mech. Ageing Devel. 41:199-210.


Mays-Hoopes, LL, Chao, W*, Butcher, H and Huang, RCC (1986).  Decreased methylation of the major long interspersed repeated DNA during aging and in myeloma cells.  Developmental Genetics 7:65-73.


Sherman, P.W., Morton, M. L., Hoopes, L. M., Bochantin, J., and Watt, J.  The use of tail collagen strength to estimate age in Belding’s ground squirrels.  Journal of Wildlife Management 49: 874-879 (1985).


Mays-Hoopes, LL, Brown, A and Huang, RCC (1983).  Methylation and rearrangement of mouse intracisternal A particle genes in development, aging, and myeloma.  Mol. Cell. Biol. 3:1371-1380.


Mays-Hoopes, LL, Cleland, G., Bochantin, J., Kalunian, D*, Miller, J.*, Wilson, W.*, Wong, M. K.*, Johnson, D*, and Sharma, O. K.  Function and fidelity of aging tRNA: In vivo acylation, analog discrimination, synthetase binding, and in vitro translation.  Mech Ageing Devel. 22:135-149 (1983).


J. Bochantin and L. L. Mays.  Age dependence of tail collagen fiber breaking time in two strains of rats.  Exper. Gerontology 16 (1): 101-106 (1981).


Lawrence, A.E.*, Readinger, J. Z.*, Ho, R. W., Ackley, S.*, Hollander, M.*, and Mays,

L. L. Rat liver lysine isoaccepting transfer ribonucleic acids shift in proportion during aging.  AGE 2:56-62 (1979).


Weber, G.*, Margetan, J.*, Finch, C. E., and Mays, L. L.  Brain transfer ribonucleic acid methyl transferases in young adult and old mice.  Experimental Gerontology 14:157-160 (1979).


Mays, LL, Lawrence, AE*, Ho, R.W., and Ackley, S*.  Age-related changes in function of transfer ribonucleic acid of rat livers.  Federation Proceedings 38:1984-1988 (1979).


Lawrence, A.*, Readinger, J.*, Ho, R. W., Ackley, S.*, Hollander, M.*, and Mays, L. Rat liver isoaccepting transfer ribonucleic acids shift in proportion during aging.  AGE 2:56-62 (1979).


Wang, R. K.-J. and Mays, L.L.  Changed isozymes of glucose-6-phosphate dehydrogenase in livers of aging rats.  Age 1:2-7 (1978).


Wang, R. K.-J. and Mays, L. L.  Opposite changes in glucose-6-phosphate dehydrogenase during aging in Sprague-Dawley and Fischer 344 rats.  Experimental Gerontology 12:117-124 (1977).


Sharma, O. K., Mays, L. and Borek, E.  Functional differences in protein synthesis between rat liver tRNA  and tRNA from Novikoff hepatoma.  Biochemistry 14: 509-514 (1975).

Sharma, O. K., Mays, L. L., and Borek, E.  Enhancement of the synthesis of a hormone-induced protein by transfer ribonucleic acids.  Journal of Biological Chemistry 248:7622-7624 (1973).


Mays, L. L., Borek, E. and Finch, C. E.  Glycine N-methyl transferase is a regulatory enzyme which increases in aging animals.  Nature 248:411-413 (1973).

Above paper was reprinted in: Dingley, R ed. Fidelity of Protein Synthesis and Transfer RNA during Aging  MSS Information Corp, 1974.


Mays, L. L. and Borek, E.  Transfer ribonucleic acid methyltransferases during hormone-induced synthesis of phosvitin.  Biochemistry 10: 4612-4614(1971).


Brooks, D., Mays, L. L., Hatefi, Y. and Young, F. E.  Glucosylation of teichoic acid: solubilization and partial characterization of the uridine diphosphoglucose polyglycerol teichoic acid glucosyl transferase from membranes of Bacillus subtilis.  Journal of Bacteriology 107:223-229 (1971).


Mays, L. L.  Isolation, characterization, and genetic analysis of osmotic mutants of Neurospora crassa.  Genetics 63:781-794 (1969).


Livingston, L. R.  Locus specific changes in cell wall composition characteristic of osmotic mutants of Neurospora crassa.  Journal of Bacteriology 99: 85-90 (1969).


Palmer, J. D., Livingston, L. and Zusy, Fr D. A persistent diurnal rhythm in photosynthetic capacity.  Nature 203:1087-1088 (1964).


Review Articles, Policy Articles, Teaching Articles


Laura L Mays Hoopes.  Top Ten Ways Men Can Help Women in Science, The Scientist,  vol 22: page 69, January, 2008.



Laura L Mays Hoopes.  H. Craig Heller (Educator Highlight),   Cell Biology Education- Life Sci Educ(CBE-LSE) 2007;6: 275-276


Laura L Mays Hoopes, “Morris Maduro,” Educator Highlight Feature, CBE-LSE  Spring, 2008,  vol 7:3-4.


Laura L Mays Hoopes, “Phoebe Lostroh,” Educator Highlight Feature, CBE-LSE summer, 2008.


Laura L Mays Hoopes, Unit 8.2. Nucleic Acid Blotting: Southern and Northern.  8.2.1-8.2.24,  Current Protocols Essential Laboratory Techniques, Wiley & Sons, Inc, 2008.


A.Malcolm Campbell, Mary Lee Ledbetter, Laura L. M. Hoopes, Todd T. Eckdahl, Laurie J. Heyer, Anne Rosenwald, Edison Fowlks, Scott Tonidandel, Brooke Bucholtz, and Gail Gottfried.  Genome Consortium for Active Teaching (GCAT): Meeting the Goals of BIO2010.   CBE-LSE 6:109-118, 2007 (summer issue).


Online resource: Johanna Hardin and LLM Hoopes, Modules for teaching undergraduate students microarray statistics developed with support by HHMI and NSF MRI equipment.


Laura L. Mays Hoopes.  Error catastrophe in mutant mitochondria.  (12 pages) SAGE-KE (American Association for Advancement of Science/Science Magazine Knowledge Environment on the internet for aging research), November, 2002;2002/45/vp6


Hoopes, L L M  Commentary: For Undergraduates, Hands-On Research and Book Learning Go Hand in Hand.  The Scientist 7 (4):10, Feb 22, 1993.


Hoopes, L. L. M.  Translation of messenger RNA to form protein.  L Hoopes editorial consultant.  Magill’s Survey of Sciences: Life Science.Volume 6, pp 2647-2653,  Salem Press, Pasadena, CA 1991.


Hoopes, Laura L. Mays.  “Thomas Cech and Phillip Altman, 1989” in The Nobel Prize Winners: Chemistry.  Frank N. Magill, editor, 3 volumes, Salem Press, Pasadena, CA, 1990.


Hoopes, L. Quick guide to the National Institutes of Health.  Council on Undergraduate Research Newsletter vol VI, 10-16 (Sept, 1985).


Hoopes, L. M.  Running an undergraduate research conference.  CUR Newsletter VII, 66-69 (Jan, 1986).


Hoopes, LLM, Moore, K.T., and Fox, C.  Diversity: How hard to attain?  CUR Newsletter IX, 36-47 (Sept, 1988)


Hoopes, LLM.  Collegiate Biology Research at Undergraduate Colleges and Universities.  CUR Newsletter X, 15-23 (May, 1990).


Hoopes, LLM and Hoopes, MT.  The State of Biology Departments in the CUR/CRAB Directory, 2nd edition.  CUR Newsletter XI, 25-33 (May, 1991).


Creative Writing

Laura L. Mays Hoopes.  Doctor, I think you’re mistaken. (humorous piece) Released July, 2006 on


Laura L. Mays Hoopes.  Breaking Through the Spiral Ceiling: An American Woman Becomes a DNA Scientist. Thirty chapter, 260 page memoir currently being circulated for consideration by presses.


Laura L. Mays Hoopes. “My Genomics Sabbatical” Goucher Quarterly. Volume 88, Fall, 2006, pp34-38.  Shortened chapter from Spiral Ceiling.  Online access after publication at:


Laura L. Mays Hoopes. “The best Christmas ever,” Daily Bulletin, Morris County, NJ. December 21, 2006.  Online access after publication at:

 Laura L. Mays Hoopes, “A crane quest behind the scenes in China.” Writers' Journal vol 28 issue 3 p 28, 34-35, 2007Winner of second prize in the Travel Writing contest. 


 Laura L. Mays Hoopes, “Through the Spiral Ceiling,” Pomona College Magazine 41(2),spring, 2007, pp44-45.  Excerpt from Breaking Through the Spiral Ceiling (see above.)  Online access after publication at:


Laura L. Mays Hoopes, “Walls in the Holy Land,” Claremont Courier, July 11,2007, pp 10-11, without last two sentences.  Republished in its entirety July 18, 2007, pp 8-9.


Laura L. Mays Hoopes, “Support of Women in Science,” Review of Every Other Thursday, AWIS Magazine 36 (2):43-44, spring, 2007.


Laura L. Mays Hoopes, “Today’s Industrial Giants Welcome Women Scientists.”  AWIS Magazine 36(2):8-11, spring, 2007. 



Laura L.Mays Hoopes, “Family-Work Issues for Women Scientists: An Interview with Diane F. Halpern.  AWIS Magazine 36 (3), summer, 2007, pp 8-10. 


Laura L Mays Hoopes, “Courageous Decision of Frank Douglas,” AWIS Magazine 36 (3), fall, 2007, pp 20-22.


Laura L Mays Hoopes, “Help Women Stay in Science,” The Scientist, vol 22: page 69, January, 2008.


 Laura L Mays Hoopes, “Women on Ice: Detecting Global Warming in the Arctic ,AWIS Magazine 37, Winter, 2008, pp16-19.


Laura L Mays Hoopes, “Charlotte Russe,” Good Old Days, vol 45 (issue 5) pp 16-17, 2008.


Laura L Mays Hoopes, The Elegance of Protein Structures.  AWIS Magazine vol 37, spring, 2008, pp11-13. 


Laura L. Mays Hoopes, “The Great Ecology Tour,”North Carolina Literary Review 17 (2008): 163-166.


Laura L Mays Hoopes, “Your Babies or Your Science: Vignettes of European Women in Science” AWIS Magazine 37(summer 2008), pp16-19.